Sedative
Analgesic
Dissociative anesthetic
PCP: Analgesia
ACP: Analgesia
ACP: Induction of sedation prior to intubation
ACP: Procedural sedation
ACP: Severe agitation or excited delirium syndrome
Hypersensitivity or allergy to ketAMINE
Unable to manage the adverse effects of ketAMINE
Conditions where elevated blood pressure may be harmful
Age < 6 months
PCP: Analgesia
Requires additional training and endorsement
ACP: Analgesia
ACP: Procedural Sedation
ACP: Anesthesia Induction
ACP: Maintenance of Anesthesia
ACP: Excited Delirium
Avoid in infants (< 6 months of age)
PCP: Not authorized
ACP: Analgesia
ACP: Procedural Sedation
ACP: Excited Delirium
Onset:
Intravenous/Intraosseous: anesthetic effects within 30 seconds
Intramuscular: anesthetic effects within 3-4 minutes
Intranasal: analgesic effects within 5-10 minutes
Duration:
Intravenous/Intraosseous: 5-10 minutes, recovery 1-2 hours
Intramuscular: 12-15 minutes, recovery 3-4 hours
Intranasal: up to 60 minutes of analgesic effects
Emergence phenomenon: confusion, delirium, excitement, hallucinations
Tachycardia and hypertension (> 10%)
Laryngospasm (< 1%)
Bradycardia and hypotension (1-10%)
Anaphylaxis (< 1%)
Hypersalivation (< 1%)
Extreme muscle rigidity or tone (< 1%)
Nystagmus, increased intraocular pressure
Apnea and respiratory depression (rare; transient reaction with rapid IV bolus dose)
Erythema, morbiliform rash, rash at injection site
Severe hypertension (systolic BP > 180 mmHg)
Subarachnoid hemorrhage or epidural hematoma with severe hypertension
Myocardial ischemia or cardiac arrhythmias